Secondary Plasma Cell Leukemia Life Expectancy

Secondary plasma cell leukemia represents an aggressive proliferative disorder associated with a poor prognosis and a shorter survival compared to mm itself.

Secondary plasma cell leukemia life expectancy.

Given that actual treatment of spcl is unsatisfactory novel therapeutic approaches are needed in order to improve outcome and quality of life in these patients. It s often related closely to multiple myeloma and sometimes presents as a secondary form of this disease more often though it occurs all on its own which is usually known as a primary diagnosis. When patients develop plasma cell leukemia after their original multiple myeloma it is secondary plasma cell leukemia. Plasma cell leukemia is more commonly seen in african americans than caucasians.

Plasma cell leukemia pcl is an aggressive form of multiple myeloma characterized by high levels of abnormal plasma cells circulating in the peripheral circulating blood. A disease involving the malignant degeneration of a subtype of white blood cells called plasma cells it is the terminal stage and most aggressive form of these dyscrasias constituting 2 to 4 of all cases of plasma cell malignancies. I had never had myeloma before it was my original diagnosis. Normal plasma cells in the bone marrow produce antibodies that fight infection.

Pcl manifests when the cancerous plasma cells are seen in the bloodstream not just in the bone marrow. Plasma cell leukemia pcl is a plasma cell dyscrasia i e. Men are at a slightly increased risk for developing plasma cell leukemia than women. Plasma cell leukemia is a rare and typically very aggressive form of blood cancer.